# Monoskin > Monoskin by Monocure Pharma is a dermatology-focused skincare brand built on formulation science and patented dermal delivery. It is India's first dermal delivery-focused skincare brand, engineering formulations for compromised, sensitive, and reactive skin using Cetosome, a US-patented transdermal nano-delivery platform. Monoskin treats skin as a biological system to understand, not a surface to improve. Every formulation is built around a single problem: many active ingredients are well studied yet fail because they never reach the skin layer where they are needed. Cetosome (US Patent US 9,084,818 B2) is a nanovesicular delivery system built on a cetyl alcohol bilayer that carries both hydrophilic and lipophilic actives through the epidermal barrier, releasing them gradually over 24 hours. Key facts: - Cetosome delivery is protected by two US patents: US 9,084,818 B2 and US 8,394,759 B2. - Controlled release window: 24 hours. Particle size begins at ~30nm. Net negative zeta potential of -20mV to -100mV. - Products: 432one, 4ZERO1, wecalm, nanogrow, Aztra-X, 08:00 AM, and Acne-Tech (Tretinoin, microsphere technology, a separate non-Cetosome system). - Clinical basis: dermatologist-tested, 234-participant trial reference. - Global presence: dermatologist partnerships across India, the United Kingdom, and Kenya. - The online store is at shop.monoskin.in (Shopify). ## Core pages - [Homepage](/): Precision dermatology overview, brand positioning, and product entry points. - [Technology](/technology): How Cetosome works. Two US patents, four platform pillars, the six-step delivery pathway, comparison vs conventional carriers, and a library of 37 verified actives. - [The Mechanism](/technology/mechanism): How Cetosome works. The barrier problem, biomimetic vesicle structure, the delivery journey, controlled 24-hour release, and targeted delivery, sourced to US Patent 9,084,818 B2. - [Our Story](/our-story): The research behind Monoskin, what the brand refuses to do (ingredient dusting, unproven actives, Rx without a doctor), and its global journey. - [Contact](/contact): Reach the Monoskin science team. ## Skin education - [Skin Education](/skin-education): Evidence-based dermatology explained simply. Hub for barrier, structure, seasonal, and condition guides. - [Skin Protection](/skin-protection): How a healthy skin barrier defends against environmental damage and what to do when it slips. - [Skin Structure](/skin-structure): The three skin layers (epidermis, dermis, hypodermis), why delivery depth changes treatment outcomes, and the thinking behind Aztra-X. - [Seasonal Care](/seasonal-care): City-by-city, season-by-season skincare routines across climates (winter barrier repair, summer SPF, monsoon sebum balance). - [Conditions Library](/conditions-library): Plain-language, evidence-based guides to common skin and hair conditions, focused on mechanism rather than symptoms. ## Conditions library guides - [Hyperpigmentation](/conditions-library/hyperpigmentation): Why dark spots form and why surface-only treatments often fail. - [Melasma](/conditions-library/melasma): A hormonally-driven, multi-layer pigmentation pattern. - [Rosacea](/conditions-library/rosacea): Persistent facial redness, triggers, and management. - [Eczema and Atopic Dermatitis](/conditions-library/eczema-atopic-dermatitis): Weakened barrier plus immune overactivity. - [Psoriasis](/conditions-library/psoriasis): A chronic autoimmune condition that accelerates skin cell turnover. - [Skin Sensitivity](/conditions-library/skin-sensitivity): What heightened reactivity signals about the barrier. - [Stress and Skin](/conditions-library/stress-and-skin): The physiological pathway linking stress to visible skin changes. - [Autoimmune Response and Skin](/conditions-library/autoimmune-response): When the immune system targets the skin. - [Acne Vulgaris](/conditions-library/acne-vulgaris): An inflammatory disorder of the pilosebaceous unit. - [Telogen Effluvium](/conditions-library/telogen-effluvium): Sudden hair shedding and recovery. - [Postpartum Hair Loss](/conditions-library/postpartum-hair-loss): A temporary, hormonally-driven shedding process. - [Androgenetic Hair Loss](/conditions-library/androgenetic-alopecia): The most common, progressive form of hair loss. ## Verified actives - [Ceramide NP / AP / EOP](/actives/ceramide-np-ap-eop): Triple ceramide complex that rebuilds the skin's lipid barrier (wecalm). - [Centella Asiatica Extract](/actives/centella-asiatica-extract): Triterpenoid botanical that calms irritation and supports tissue repair (432one). - [Panthenol (Pro-Vitamin B5)](/actives/panthenol-pro-vitamin-b5): Humectant and metabolic repair cofactor (4ZERO1, wecalm, nanogrow). - [Hyaluronate Sodium](/actives/hyaluronate-sodium): Humectant hydration across molecular weights (432one). - [Nigella Sativa (Black Seed Oil)](/actives/nigella-sativa-black-seed-oil): Thymoquinone-driven anti-inflammatory scalp support (nanogrow). - [Anagain](/actives/anagain): Pea sprout extract targeting the anagen growth phase (nanogrow). - [Caffeine](/actives/caffeine): Counteracts DHT at the follicle, the strongest evidence anchor for nanogrow's non-Minoxidil positioning. - [Azelaic Acid 15%](/actives/azelaic-acid-15): Tyrosinase inhibitor for pigmentation and acne (Aztra-X). - [Tranexamic Acid 3%](/actives/tranexamic-acid-3): Plasminogen inhibitor that interrupts the inflammation-to-pigment cascade (Aztra-X). - [Glycolic Acid 1% + Microbeads](/actives/glycolic-acid-1-microbeads): Dual chemical and physical exfoliation (08:00 AM). - [Dual Vitamin E System](/actives/dual-vitamin-e-system): Tocopherol plus tocotrienol for broad lipid-phase antioxidant coverage (wecalm). - [Glycoside Licorice Extract](/actives/glycoside-licorice-extract): Gentle tyrosinase inhibition and brightening (432one). - [Tretinoin Gel USP 0.025%](/actives/tretinoin-gel-usp-0-025): Gold-standard retinoid with microsphere controlled release (Acne-Tech). ## Campaign - [Skin Health Awareness Campaign](/skin-campaign): Go See the Doctors. Only 5% of online skin discourse comes from a dermatologist; Monoskin works with dermatologists across India, the UK, and Kenya to put real expertise back in view. ## Optional - [Privacy Policy](/privacy-policy): How Monoskin collects, uses, and protects personal information. - [Terms of Service](/terms-of-service): Terms governing use of the Monoskin website, products, and services. - [Shop](https://shop.monoskin.in/collections/all-products): The Monoskin online store (external, Shopify).